The Ke Yuan lab at Boston Children's Hospital and Harvard Medical School will dissect the critical role of pericytes during angiogenesis and aim to understand abnormal vascular remodeling in pulmonary arterial hypertension (PAH) and other pulmonary vascular diseases. The ultimate goal is to identify potential therapeutic targets that could be exploited for the development of new drugs capable of preventing abnormal vessel remodeling and obliteration in PAH.
Breaking News
Congratulations to Timothy Klouda, Yunhye Kim and Seung-Han Baek on the new research paper published in The EMBO Journal, entitled " Specialized pericyte subtypes in the pulmonary capillaries". Pericytes were first described in the 1870s. A century and a half later, our group can now use Higd1b to study pericytes exclusively, apart from other cells. This result could open new therapeutic pathways for PAH and several other pulmonary issues. These findings also suggest the groundbreaking discovery of a novel mouse model for studying pericytes and PAH.
Read the story here: https://answers.childrenshospital.org/pericytes-marker/​
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